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Betahistine HCI Tablets IP 24 mg

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Description

Betahistine HCI Tablets IP 24 mg is a medication commonly used to treat symptoms associated with Meniere’s disease, a disorder of the inner ear that causes vertigo (dizziness), tinnitus (ringing in the ears), and hearing loss. Betahistine is a histamine analogue that works by improving blood flow in the inner ear, which helps to reduce the pressure and fluid build-up that contributes to the symptoms of Meniere’s disease.

Active Ingredient:

  • Betahistine Hydrochloride (HCI) 24 mg

Mechanism of Action:

Betahistine works by acting on the histamine receptors (specifically H1 and H3 receptors) in the inner ear and the brain. It:

  • Improves microcirculation in the inner ear, leading to a reduction in pressure.
  • Decreases the frequency and intensity of vertigo by reducing the fluid accumulation in the inner ear, which can disrupt balance.
  • Increases the release of histamine, which helps dilate blood vessels in the ear, improving circulation and reducing symptoms.

Indications:

Betahistine HCI 24 mg is primarily used to treat:

  • Meniere’s disease, which causes:
    • Vertigo (severe dizziness)
    • Tinnitus (ringing in the ears)
    • Hearing loss
  • Other vestibular disorders, which may result in balance issues or dizziness.

Dosage and Administration:

  • Adults: The typical dosage is 24 mg three times daily, depending on the doctor’s recommendation and the severity of symptoms.
  • The tablet should be taken with food to reduce potential stomach upset.
  • The dosage may be adjusted based on the individual’s response to treatment.
  • It is important to follow the doctor’s instructions for exact dosing and duration.

Side Effects:

Betahistine is generally well-tolerated, but like any medication, it may cause some side effects. Common and serious side effects include:

  1. Common Side Effects:
    • Headache
    • Indigestion or nausea
    • Drowsiness or fatigue
    • Mild stomach discomfort
  2. Serious Side Effects (less common):
    • Allergic reactions: Rash, itching, or swelling (especially of the face/tongue/throat)
    • Severe dizziness or fainting
    • Heart-related issues: Irregular heartbeat or chest pain (rare)
    • Gastrointestinal bleeding (very rare)

Precautions:

Before taking Betahistine, inform your doctor if you have:

  • Peptic ulcer or a history of stomach ulcers, as Betahistine can increase stomach acid production.
  • Asthma, since Betahistine can worsen asthma symptoms in some individuals.
  • Liver or kidney disorders, as Betahistine should be used cautiously.
  • Allergies to Betahistine or any of its ingredients.
  • Pregnancy and Breastfeeding: Betahistine should only be used during pregnancy if clearly needed, and it should be used with caution in breastfeeding women. Always consult with a doctor before taking the medication.

Drug Interactions:

Betahistine can interact with the following:

  • Antihistamines: May reduce the effectiveness of Betahistine.
  • Monoamine oxidase inhibitors (MAOIs): These may increase the side effects of Betahistine.
  • Other medications affecting blood pressure: Betahistine can affect the blood pressure, and its interaction with blood pressure medication should be monitored.

Storage:

  • Store Betahistine tablets in a cool, dry place, away from direct sunlight.
  • Keep out of the reach of children.
  • Do not use the medication after the expiration date on the packaging.

Important Notes:

  • Always follow the prescribed dosage schedule. Do not take more or less than prescribed, and do not stop taking the medication abruptly without consulting your doctor.
  • If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double the dose to make up for a missed one.
  • Contact your doctor if you experience any side effects or if your symptoms worsen.

Summary:

Betahistine HCI Tablets 24 mg are primarily used to treat symptoms associated with Meniere’s disease, such as vertigo, tinnitus, and hearing loss. It improves inner ear circulation, reducing pressure and fluid buildup. Betahistine is generally well-tolerated, but it may cause side effects like nausea, headache, and stomach discomfort. It is important to follow the prescribed dosage and consult with a healthcare provider before starting the medication, especially if you have conditions such as peptic ulcers or asthma.

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